Hair Regeneration

Hair loss Facts.Hair loss affects approximately 40% of men and 20% of women aged 50 and over. In the US there are an estimated 40 million men and 12 million women suffering from some degree of baldness. The estimated market size for hair regeneration products and treatments is over $1 billion for both men and women but only 2% of patients suffering hair loss currently seek any treatment.
Existing Treatments.
Hair loss treatments available today a few and far between, so far there is only two medicines which have been licensed for use as a Male hair loss product. 1 Propecia & 2 Regaine.
Propecia is the more successful treatment out of the two and has many papers and happy customers that have used the product who have either stop hair loss in its tracks or regained lost hair.
Regaine can be bought over the counter at most pharmacies & supermarkets and has worked on a smaller percentage to some degree.Hair Cloning
But now a company in Manchester called Intercytex have been busy working on cloning, hair cloning that is. Already phase 1 & 2 of the hair cloning trials have been completed and are showing some promising results.
The ICX-TRC procedureA small sample of hair follicles is taken from the patient during a simple 30 minute operation carried out under local anaesthetic at a hair or skin clinic. The clinic sends the biopsy to Intercytex’ GMP compliant manufacturing facility where the DP cells are dissociated from the rest of the follicle. These cells are cultured and expanded in proprietary media over three weeks and subsequently returned to the clinic in a sterile suspension.sing a specialised delivery system, the DP cells are microinjected intradermally into the patient’s scalp. The treatment is performed under local anaesthetic and comprises a single procedure of superficial injections, each injection delivering a minute volume of media containing DP cells. These cells are able to stimulate the generation of new hairs when injected in close proximity to the epidermal cells which generate the hair. Following the procedure, new hair growth should become evident after approximately three months.ICX-TRC clinical and commercial developmentPhase I clinical trials (safety) have been completed in seven volunteers at a single UK transplant centre. No safety issues have arisen and five out of seven patients have shown increased hair numbers. A Phase II study, which was conducted by Dr Bessam Farjo in Manchester, is now complete. This trial was designed to examine the effect of different DP delivery techniques and methods to ensure that the epidermal cells were in the correct state to respond to the signals and produce new hairs.In this study, subjects were injected 900 times with 1µl aliquots of DP cells in a large area which was photographed at the end of the study. Subjects were also injected in a smaller area, divided into two sections - counts were obtained by shaving and photographing the two small sections of scalp, injecting them multiple times (either 1 injection of 50 µl or 50 injections of 1 µl) with living DP cell suspension and then applying a specialised image analysis system to provide a total hair count. In these small sections, all 19 subjects in the trial were treated using a range of injection and scalp pre-stimulation techniques; the first 6 subjects were injected without stimulation of the scalp. In the remaining 13 subjects the resident hair producing (epithelial) cells were stimulated at the time of delivery of the DP cells in one of the two treatment sites.13 subjects completed the 48-week trial with 6 subjects lost to follow-up. Of the 13 subjects completing the trial the data showed that:• 65% (11/17) of the treated sites in the non-stimulated group responded to the treatment by increasing numbers of hairs of all sizes• 71% (12/17) of the treated sites in the non-stimulated group responded to the treatment by increasing numbers of hairs over 30 micron in diameter• 78% (7/9) of the treated sites in the stimulated group responded to the treatment by increasing numbers of hairs of all sizes• 100% (9/9) of the treated sites in the stimulated group responded to the treatment by increasing numbers of hairs over 30 micron in diameter• The overall take rate (number of hairs produced per 100 injections) in the stimulated areas waso 40% (n=6) for hairs of all sizeso 18% (n=6) for hairs over 30 micron in diameter
The results of these trials are a big leap in finding a permanent cure for hair loss.
Dr Bessam Farjo, the Principal Investigator for this study, said “We have learned a lot from this trial, including the different ways in which these cells can be delivered and that it is possible to do one thousand of these injections in a relatively short period of time and at little discomfort to the patient. I am very encouraged by this data both in the increase in the total number of hairs in the treated site but more importantly by the increase in thicker hairs, those over 30 micron.”

Healthy Hair Tips, Myths and Misconceptions

Our glorious hair. We sometime shave, curl, spike, dreadlock, blow dry, braid, and spray it within an inch of it’s life. We spend untold money on hair care products. Not to mention the world is awash in so called healthy hair tips, myths and misconceptions. Let’s discuss a few of them.

Hair Misconception #1: A stress filled life leads directly to subsequent hair loss.

Reality: It’s a fact we are all losing hair daily. Whether we are stressed to the max or not. On average you lose anywhere between 35 to 135 hairs each day. So maybe a few more strands might fall out if you're all tense and stressed out. But unless you have been pulling your hair out by the roots, it will all grow back!

Hair Misconception #2: Using several shampoos keeps your hair healthy.

Reality: Of the so called healthy hair tips this one makes me laugh it’s so far fetched. Hair doesn’t remember what shampoo was used on it last. It’s basically just dead cells. So how’s it gonna know what kind of shampoo you’re using? But it is true that people with different hair types need to use shampoos suited to their type of hair. Focus on that rather than rotating shampoo.

Hair Misconception #3: There's nothing you can do for fine hair to keep it from going limp.

Reality: Two words: Hot rollers. They make it easy to add body to fine hair. Afterwards just apply mousse and brush out well.

Hair Misconception #4: Coloring is hard on your hair.

Reality: Nonsense! If that was the case most hair stylists would be out of a job. Coloring is safe if you know what you’re doing and follow the instructions to the letter. (That’s one of the healthy hair tips to remember.)

It also helps to use gentle coloring products and conditioners and shampoos specifically designed for colored hair. In fact it’s wise to use extra conditioner whenever you wash your colored hair.

Hair Misconception #5: Pull a gray hair and it will be replaced by more than one.

Reality: Ever heard that? No way is that true. Still you should never pull out hair by the roots. You can scar yourself or you might develop a scalp infection trying that. It’s better to banish the gray by coloring your hair.

Hair Misconception #6: All hair reacts to humidity in the same way.

If you have curly hair you don’t need me to point out that this is a big lie. Once the humidity hits it, uncontrollable curls or worse, the dreaded frizzys results. To strike back you need a product that will lock down the cuticle layer. One that blocks out unwanted moisture. So look for styling products with words like anti-humectant, smoothing, anti-humidity on the label.

Hair Misconception #7: It’s best to shampoo twice for clean hair.

Reality: This is just not so. In fact over use of shampoos can damage your hair. Unless your hair is extremely oily shampooing once should suffice.

How about those seven healthy hair care tips?How about if we continue our discussion of healthy hair care tips with an overview about how to go about the task of repair of damaged hair.

Author Info:
How about if we continue our discussion of healthy hair care tips with an overview about how to go about the task of repair of damaged hair.

Hair Loss Basics (Why people lose hair?)

Managing Hair Loss: Hair Loss Basics

Reasons for Hair Loss

Photo by: freeparking

The most common reasons for losing hair are as under:

The physical reasons:

The physical reason for losing hair are linked to your hair style, for example hair pulled so tightly that it places tension on the scalp can result in a condition called traction alopecia. Traction alopecia can be permanent if the style is worn for a long enough time that it damages the hair follicles. . Having your hair chemically treated, such as getting your hair colored, bleached, straightened, or permed, can make the hair break off or fall out temporarily. Excessive use of hair dryers for styling or always sticking to the same hair style makes the hair to be pressed too much. Changing your hair style early is the best thing to do in this case.

Poor nutrition:

Eating disorders or poor eating can cause hair loss. This happens because your body does not get enough protein, vitamins, and minerals to sustain hair growth. Vegetarians might also lose their hair because they don't get enough protein from non-meat sources.

Skin & Scalp Diseases:

Hair loss can be related to some skin diseases & scalp diseases as well, such as in mycosis baldness would usually appear in the type of hairless inflammatory focus (es). The treatment in such cases means giving the patient oral and local antimycotic remedies.

Androgenetic alopecia:

Among adults, the most common cause of hair loss is androgenetic alopecia. This condition is caused by hormones called androgens and genetics. Sometimes, the hair loss can start as early as the mid-teen years. It also can occur in people who take steroids like testosterone to build their bodies.

Systemic illnesses:

Endocrine (hormonal) conditions, such as uncontrolled diabetes or thyroid disease, can interfere with hair production and cause hair loss. People with lupus can also lose hair. The hormone imbalance that occurs in polycystic ovary syndrome can cause hair loss in teen girls as well as adult women. The treatment of hair loss in such cases depends on the treatment of the basic illness that actually caused hair loss.

Baldness because of drugs:

Some medications can cause hair loss as a side effect. Diet pills that contain amphetamines also can cause hair loss. Chemotherapy drugs for cancer are the most well-known medications that can cause hair loss.

Hair Loss Facts & Fiction

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Hair Loss Treatments for Men

Hair loss is a very common problem and the number of proven treatments is limited. Propecia is one of those hair loss treatments that has gone through extensive clincial trials and shown some significant results.

Read more on the hair treatments for men on the Hair Treatment website.

Hair Loss Tablets

There are many hair loss products & treatments that lay claim to grow your hair back or stop further hair loss, just search through google and you will come across hundreds. But there is only a few products that don't just claim but are actually proven to grow your hair back.

Propecia: The most common hair loss tablet on the market today, has been approved by the FDA and has also gone through clinic trials proving not only can it stop hair from falling out. It also can re-grow hair that has been lost.

Regaine(minoxidil): or Rogaine as its know in America, has also been approved by the FDA. This treatment does not need a prescription and can be bought from your local chemist to your supermarket. It is a topical lotion which has also been proven to stop hair loss in clinical trials.

These two products are the only to proven products which are sold worldwide today, Im sure more hair treatment tablets will come on the market soon.

Androgenetic Alopecia - A comprehensive guide

Androgenetic alopecia is the most common cause of hair loss in men and women and starts affecting people right from their 20's sometimes. Read more about androgenetic alopecia in detail here.

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Finasteride

Finasteride was approved initially in 1992 as Proscar, a treatment for prostate enlargement, but the sponsor had studied 1 mg of finasteride and demonstrated hair growth in male pattern hair loss. On December 22, 1997, the FDA approved finasteride to treat male pattern hair loss.

Therefore Finasteride (Propecia) was the first oral drug licensed for the treatment of Male Baldness.

Finasteride (propecia) drastically reduces the effect of the enzyme 5 alpha reductase (type II), and in doing so,reduces the conversion of testosterone to dihydrotestosterone (DHT), which it is responsible for in the hair cell. It is DHT that is one of the major culprits for hair loss in genetically determined hair cells.

DNA test for hair loss

BACKGROUND: Most men resign themselves to the fact they might lose their hair, but how many women need to worry about losing their hair? hair treatment4u says hair loss affects 21 million women in the United States alone. Baldness occurs when hair falls out and new hair doesn't take its place. Normally, hair grows at an average rate of about half an inch per month for two to six years, then rests and then falls out. Soon after that, a new hair begins to grow in its place. At a given point in time, 85 percent of your hair is growing and 15 percent is resting, according to the National Institutes of Health. Unlike men, women with female pattern baldness can begin losing their hair at any age through 50 or later, may not be genetically predisposed to hair loss and may not fall prey to the recognizable thinning over the top of the scalp.

CAUSES: The cause of female baldness is not well understood, but is associated with genetics, aging and levels of endocrine hormones. In particular, androgens, or male sex hormones, are associated with hair loss. As in men, the most likely cause of hair loss is androgenetic alopecia, or an inherited sensitivity to the effects of androgens on hair follicles in the scalp. Other causes include trichotillomania, or compulsive hair pulling; alopecia areata, a disorder that causes patchy hair loss ranging from diffuse thinning to extensive balding with "islands" of retained hair; triangular alopecia, or loss of hair in the temporal areas that sometimes begins in childhood; scarring alopecia, or hair loss due to scarring of the scalp area typically involving the top of the head; and telogen effluvium, a common type of hair loss that takes place when a large portion of hair shifts into the "shedding" phase. Telogen effluvium can be hormonal, nutritional, drug associated or stress-associated. Menopause can be associated with both scarring alopecia and telogen effluvium.

TREATMENT: Female pattern hair loss can begin as early as the late teens to the early 20s in women who have experienced early puberty, says the International Society of Hair Restoration Surgery. If left untreated, this type of hair loss can progress to a more advanced form. Treatment is also recommended for women whose self-esteem is damaged by hair loss. The only drug approved by the Food and Drug Administration (FDA) to treat female pattern baldness is minoxidil (Rogaine). For women, the FDA recommends the two percent concentration. Minoxidil may help hair grow in 20 to 25 percent of women, and in the majority may slow or stop the hair loss process. Another option for women suffering from baldness are hair transplants. Hair transplants involve removing tiny plugs of hair from healthily growing areas and placing the hair in balding areas. The procedure usually requires multiple sessions and can be expensive. In addition, it can cause minor scarring and carries a risk of skin infection; however, results are often pleasing and permanent.

DETECTION: In order to effectively treat baldness, experts recommend a physician's diagnosis. It is important to catch and treat baldness as early as possible to prevent further hair loss. A new genetic test may help women treat baldness before its effects even show. It's called HairDX and through it doctors can predict whether or not a woman will have significant hair loss. After swabbing the inside of your mouth, the doctor sends the sample off to the laboratory for testing. Three to four weeks later, the results are sent back. The test costs about $150.

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